Liver cancer symptoms are very diverse. However, as a rule, there are common symptoms of «malignant disease», manifestation of which depends on the variations of clinical course of the neoplasm.

In a typical aspect of disease leading symptoms are noted such ones as progressive weakness, adynamia, appetite loss, cachexia, often nausea and vomiting. There is a carebaria and the constant pain in the right subcostal area, anemia develops. Liver quite rapidly increases in size, with its lower edge often determined on the level of the navel and below; with palpation it is moderately painful, stiff, hilly; sometimes is determined an isolated tumor node.

With the liver cancer development against the background of cirrhosis, symptoms of malignant neoplasms are prevalent in the clinical presentation of the disease; deterioration of the patient makes progress rapidly, increases pain in the liver, appears ascites, jaundice, fever, arises frequent nasal bleeding, often found skin telangiectasis.

In some cases of the primary liver cancer is a high non-treatment fever; symptoms of liver lesion appear later in these cases.

Asymptomatic form of primary liver cancer often goes like a chronic hepatitis B, without constant and typical clinical signs of cancer. In some cases, the clinical presentation of primary liver cancer may include symptoms of complications or signs of dissemination of tumor.

In the clinical symptomatology of complications are typical: obstructive jaundice (compression of main bile duct tumor or its metastases), splenomegaly, ascites, enlargement of subcutaneous veins of the front abdominal wall, gastrointestinal bleeding (compression of portal vein), and signs of rupture of the tumor, spontaneous or under the influence of minor injuries with intraperitoneal bleeding and subsequent peritonitis.

Metastatic liver cancer is mostly detected in the liver (intraorganic metastasis), in lymph nodes of the porta and omentulum, in splanchnic as well as other organs (lungs, pleura, peritoneum, kidneys, pancreas, bones).