Treatment of primary liver cancer is currently being conducted by combined methods. The main method is a radical surgical intervention (typical lobectomy or hemihepatectomy, atypical resections of the liver) in combination with chemotherapy (methotrexate, thio-TEF, 5-fluorouracil) with the introduction of drugs through of umbilical vein or hepatic artery. However, the possibility of a radical operation is only available for one of five patients (depends on liver cancer symptoms and diagnosis).

In a specially equipped medical centers performed a liver transplant. Radiation therapy is usually not effective and can be used only in the postoperative period. There are currently carried out extensive researches to determine the effectiveness of immunization against hepatitis B as a way to prevent hepatocellular carcinoma.

The forecast for operated on the primary liver cancer, unfortunately, is not optimistic, no more than 9-19% of patients who experienced surgery are living up to 5 years after surgery. The transplantation of the liver is the best perspective for today.